gcthomas
New member
Shannon doesn't include a measure of meaning, so your accusation is unfounded. Feel free to quote me otherwise if you can.
Good - so you agree that any discussion of 'meaning' on DNA with or without mutations has to take place outside of Shannon's Noisy Channel Theorem, such as when you describe mutations as "bad" information. ("'What works' defines what is good.")
So, what works is what allows the organism to survive and reproduce and pass on the DNA. If the DNA doesn't 'work' then that new information is either removed from the gene pool or it has a low-significance effect. Since mutations can undo the damage of a previous mutation, then it is self evident that mutations can increase the organism's fitness, so unless you have the unfounded belief that DNA started perfect in a divine creation event, a significant proportion of all mutations are beneficial. They are, in your terms 'good'.
The human mutation that allowed a portion of humanity to digest cow's milk is good. The gene that causes sickle-cell anaemia protects against malaria, so that's good. The mutation that allowed the digestion of alcohol is good for those who have it. There is a recent mutation in the US Midwest, where a family have unusually high bone density, such that one member had a major road crash and no broken bones. No-one in the family had ever had a broken bone and do not suffer from age related skeletal degeneration: this low-density lipoprotein receptor-related protein 5 mutation is good, and medicines are being developed to try to reproduce the effect. It is a shame that humans weren't created with this form of the gene to begin with. :idunno:
Are you still going to insist that all mutations are 'bad'?