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Maternal COVID-19 Vaccination and Its Potential Impact on Fetal and Neonatal Development
however, errors were found in their analysis [10], and a follow-up re-analysis of the data revealed a cumulative incidence of spontaneous abortion of 7–8 times higher than the original author’s calculations, which was statistically higher than the typical average for pregnancy loss during the equivalent time periodMaternal COVID-19 Vaccination and Its Potential Impact on Fetal and Neonatal Development - PMC
Vaccines have been developed under accelerated timelines to combat the COVID-19 pandemic caused by the SARS-CoV-2 coronavirus. Although they are considered the best approach for preventing mortality, when assessing the safety of these vaccines, ...
www.ncbi.nlm.nih.gov
lipid nanoparticle (LNP)
Concerns were raised years ago regarding the safety of LNPs due to their biodistribution. For example, they were found to disperse to the ovaries in experimental mice [18]. Pfizer’s own pharmacokinetic studies of a surrogate vaccine containing ALC0315 and ALC0159 LNPs demonstrated that they dispersed over a 48 hours period to many rat endocrine and immune organs including the ovaries, adrenals, bone marrow, liver and spleen [19].